Road signs very similar to uk. Remember speed limits are in KPH, if you hire a van derivitive such as a Fiat Doblo, the max speed limit is 80KPH. Remember to drive on the right:D The main thing to remember is to always expect the unexpected from other drivers. They will come out of side roads and look after they have come out, they will jump red lights, so if yours is on green just have a quick look to your left before you move off. At night some of the traffic lights will flash either red or amber, you treat these as you can go through but with caution, if your lights are flashing red you must give way to others coming through across you. On roundabouts you must give way to those entering the roundabout.
You will get motorbikes, and sometimes cars, coming at you on the wrong side of the road. They are usually going to turn down a side road, or have just come out of one, they will avoid you but it is a bit of a shock when it first happens.
Expect to see some 'wonderful' sights such as 4 or even 5 people on one scooter.
If you have an accident, even a small bump, you must leave tha cars where they are and call the Police/Jandarme.
There is far less traffic here than in the UK so no traffic jams to worry about.
After a short while you will get used to the driving conditions here, we quite enjoy driving over here. Just be road wise and observant and you will enjoy driving here, trust me I'm a ........?

Hope this helps and I am sure others over here will add anything I have missed.
Eric